Store: 865-523-9763    |    Email:  

Misty’s PET DEPOT® is located in Knoxville, TN with over 4300 sq ft of pet supplies. Misty’s is stocked with everything imaginable for all kinds of pets…cats, dogs, fish, small animals and reptiles. Our store focuses on premium, all natural and holistic brands of food which are always freshly stocked and competitively priced. We pride ourselves by carrying all natural products such as shampoos and supplements and providing unique and eclectic pet items such as cat towers, pet beds and crates just to name a few.

Locally owned by father/daughter team, Bill and Misty Lifford, who have been East Knoxville residents for over 60 years, they are committed to providing the community with excellent customer service, a clean, organized store and most importantly a great experience for you and your pet.

Come on in to Misty’s and bring in your fur babies (on a leash, please)! Let them pick out their toys and treats and meet our in house kitties, Sam Sam and Oreo. Find out why we are your “Neighborhood Pet Store”.

Our Store Features


With countless options, Misty’s PET DEPOT is the NATURAL PET FOOD HEADQUARTERS℠


We offer a large variety of pet supplies to choose from, so you can keep your pet healthy and happy


Let our experts recommend the right service for your pet


Misty’s PET DEPOT rewards membership entitles you to exclusive offers and savings on all the supplies you want


Our location works with local shelters to provide homes to pets in need


Our professional and caring staff will ensure that you and your pet receive the best customer service possible

SIGN UP for our FREE REWARDS program and get tons of great deals on the merchandise you want for your pets!

FREE Rewards membership entitles you to exclusive offers through our monthly E-Coupon campaign that can save you hundreds of dollars each year! You will also automatically receive discounts on ALL our in-store specials and promotions every day.

These coupons are sponsored by the manufacturers all competing for your business. You can sign up in the store, or fill out the form online and we’ll add you to the list.


The Misty’s PET DEPOT Blog features helpful care tips, the latest pet industry news, advice for new pet parents, and much more!


Brands We Recommend*

    *Not all brands are carried in store. Please check our “Pet Foods We Carry” page to view the full line of brands we carry.